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\sffamily \bfseries
 \title
[Proteins and Macromolecules\hspace{0.75cm}]
{\it Proteins and Macromolecules}
\author
[Snehalatha Kaliappan]
{\small Talk to a Teacher \\ http://spoken-tutorial.org\\ National Mission on Education
  through ICT \\ http://sakshat.ac.in \\ [0.4cm]
Snehalatha Kaliappan\\ IIT Bombay \\ [0.4cm]
{\small 14 April 2014} \\[0.4cm]
}

\begin{frame}
\titlepage
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\begin{frame}
\frametitle{Learning Objectives} \pause
\begin{itemize}[<+-|alert@+>]
\item Load structures of proteins from {\it \small Protein Data Bank (PDB)}
\item Download .pdb files from {\small PDB} database
\item Display secondary structure in various formats 
\item Highlight hydrogen bonds and disulfide bonds
\end{itemize}
\end{frame}


\begin{frame}
\frametitle{Pre-requisites} \pause
\begin{itemize}[<+-|alert@+>]
\item Familiar with basic operations from Jmol Application window.
\item If not, watch the relevant tutorials available at {\color{blue} http://spoken-tutorial.org} 
\end{itemize}
\end{frame}


\begin{frame}
\frametitle{System Requirements} 
\begin{itemize}[<+-|alert@+>]
\item Ubuntu OS version 12.04
\item Jmol version 12.2.2
\item Java(JRE) version 7 \\(Sun Microsystems)
\item Mozilla Firefox Browser 22.0
\end{itemize}
\end{frame}

\begin{frame}
\frametitle{Jmol for Biomolecules}
Structure analysis of large biomolecules  
\begin{itemize}
\item {\it Proteins and Macromolecules}
\item {\it Nucleic acids (DNA and RNA)}
\item {\it Crystal structures and Polymers}
\end{itemize}
\end{frame}

\begin{frame}
\frametitle{Summary}
\begin{itemize} 
\item Load structures of protein from {\it \small  Protein Data Bank (PDB)}
\item Download .pdb files from the database
\item View {\small 3D} structure of insulin using {\it \small PDB code (4EX1)}
\end{itemize}
\end{frame}

\begin{frame}
\frametitle{Summary}
\begin{itemize} 
\item View protein structure without water molecules
\item Display secondary structure in various formats
\item Highlight hydrogen bonds and disulfide bonds 
\end{itemize}
\end{frame}     

\begin{frame}
\frametitle{Assignment}
\begin{itemize} 
\item Download the .pdb file of human Hemoglobin from {\it \small PDB} database
\item Show secondary structure in cartoon display
\item Highlight the {\it Porphyrin} units of the protein 
{\small {\color{blue} http://www.rcsb.org/pdb/home/home.do}}
\end{itemize}
\end{frame}

\begin{frame}
\frametitle{About the Spoken Tutorial Project}
\begin{itemize}
\item Watch the video available at {\color{violet} http://spoken-tutorial.org /What\_is\_a\_Spoken\_Tutorial}
\item It summarises the Spoken Tutorial project \pause
\item If you do not have good bandwidth, you can download and watch it
\end{itemize}
\end{frame}

\begin{frame}
\frametitle{Spoken Tutorial Workshops}
The Spoken Tutorial Project Team
\begin{itemize}
\item Conducts workshops using spoken tutorials
\item Gives certificates to those who pass an online test
\item For more details, please write to {\color{violet} contact@spoken-tutorial.org}
\end{itemize}
\end{frame}

\begin{frame}
\frametitle{Acknowledgements}
\begin{itemize}
\item Spoken Tutorial Project is a part of the Talk to a Teacher project
\item It is supported by the National Mission on Education through
  ICT, MHRD, Government of India
\item More information on this Mission is available at
{\color{violet} http://spoken-tutorial.org /NMEICT-Intro}
\end{itemize}
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\end{document}


